Refolo, Lorenzo M. : rechercher sur Z-Library

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1

Targeting APP metabolism for the treatment of Alzheimer's disease

Kumar Sambamurti, John Hardy, Lorenzo M. Refolo, Debomoy K. Lahiri

Journal:

Drug Development Research

Année:

2002

Langue:

english

Fichier:

PDF, 191 KB

english, 2002

2

Common Alzheimer’s Disease Research Ontology: National Institute on Aging and Alzheimer’s Association Collaborative Project

Lorenzo M. Refolo, Heather Snyder, Charlene Liggins, Laurie Ryan, Nina Silverberg, Suzana Petanceska, Maria C. Carrillo

Journal:

Alzheimer's & Dementia

Année:

2012

Langue:

english

Fichier:

PDF, 3.78 MB

english, 2012

3

Strategies for drug discovery for cognitive aging and alzheimer’s disease

Howard M. Fillit, Alan W. O’Connell, Lorenzo M. Refolo

Journal:

Journal of Molecular Neuroscience

Année:

2002

Langue:

english

Fichier:

PDF, 55 KB

english, 2002

4

Statin therapy for Alzheimer’s disease

Suzana S. Petanceska, Steven DeRosa, Vicki Olm, Nichole Diaz, Ali Sharma, Tara Thomas-Bryant, Karen Duff, Miguel Pappolla, Lorenzo M. Refolo

Journal:

Journal of Molecular Neuroscience

Année:

2002

Langue:

english

Fichier:

PDF, 103 KB

english, 2002

5

Tau and Alzheimer’s disease

Howard M. Fillit, Lorenzo M. Refolo

Journal:

Journal of Molecular Neuroscience

Année:

2002

Langue:

english

Fichier:

PDF, 49 KB

english, 2002

6

Atorvastatin-induced activation of Alzheimer's α secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding

S. Parvathy, Michelle Ehrlich, Steve Pedrini, Nichole Diaz, Lorenzo Refolo, Joseph D. Buxbaum, Alexey Bogush, Suzana Petanceska, Sam Gandy

Journal:

Journal of Neurochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 150 KB

english, 2004

7

Changes in apolipoprotein E expression in response to dietary and pharmacological modulation of cholesterol

Suzana S. Petanceska, Steven DeRosa, Ali Sharma, Nichole Diaz, Karen Duff, Steven G. Tint, Lorenzo M. Refolo, Miguel Pappolla

Journal:

Journal of Molecular Neuroscience

Année:

2003

Langue:

english

Fichier:

PDF, 450 KB

english, 2003

8

Apolipoprotein E4 as a target for developing new therapeutics for Alzheimer’s disease

Lorenzo M. Refolo, Howard M. Fillit

Journal:

Journal of Molecular Neuroscience

Année:

2004

Langue:

english

Fichier:

PDF, 71 KB

english, 2004

9

Drug discovery for Alzheimer’s disease

Lorenzo M. Refolo, Howard M. Fillit

Journal:

Journal of Molecular Neuroscience

Année:

2004

Langue:

english

Fichier:

PDF, 75 KB

english, 2004

10

Amyloid precursor protein compartmentalization restricts β-amyloid production

Swetal Gandhi, Lorenzo M. Refolo, Kumar Sambamurti

Journal:

Journal of Molecular Neuroscience

Année:

2004

Langue:

english

Fichier:

PDF, 169 KB

english, 2004

11

Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid β peptide levels

Javier Pacheco-Quinto, Elena B. Rodriguez de Turco, Steven DeRosa, Altovise Howard, Felix Cruz-Sanchez, Kumar Sambamurti, Lorenzo Refolo, Suzana Petanceska, Miguel A. Pappolla

Journal:

Neurobiology of Disease

Année:

2006

Langue:

english

Fichier:

PDF, 336 KB

english, 2006

12

Cholesterol, oxidative stress, and Alzheimer’s disease: expanding the horizons of pathogenesis

Miguel A Pappolla, Mark A Smith, Tara Bryant-Thomas, Nicolas Bazan, Suzana Petanceska, George Perry, Leon J Thal, Mary Sano, Lorenzo M Refolo

Journal:

Free Radical Biology and Medicine

Année:

2002

Langue:

english

Fichier:

PDF, 244 KB

english, 2002

13

Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model

Lorenzo M. Refolo, Miguel A. Pappolla, Brian Malester, John LaFrancois, Tara Bryant-Thomas, Rong Wang, G.Stephen Tint, Kumar Sambamurti, Karen Duff

Journal:

Neurobiology of Disease

Année:

2000

Langue:

english

Fichier:

PDF, 166 KB

english, 2000

14

Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model: Volume 7, Number 4 (2000), pages 321–331

Lorenzo M. Refolo, Miguel A. Pappolla, Brian Malester, John LaFrancois, Tara Bryant-Thomas, Rong Wang, G.Stephen Tint, Kumar Sambamurti, Karen Duff

Journal:

Neurobiology of Disease

Année:

2000

Langue:

english

Fichier:

PDF, 19 KB

english, 2000

15

Hypercholesterolemia accelerates amyloid pathology in a transgenic mouse model of Alzheimer's amyloidosis

Lorenzo M. Refolo, Rong Wang, Steven G. Tint, Kumar Sambamurti, John La Francois, Karen Duff

Journal:

Neurobiology of Aging

Année:

2000

Langue:

english

Fichier:

PDF, 173 KB

english, 2000

16

Tau pathobiology in transgenic mouse models

Karen Duff, Lorenzo M. Refolo, Michael Hutton, Peter Davies

Journal:

Neurobiology of Aging

Année:

2000

Langue:

english

Fichier:

PDF, 195 KB

english, 2000

17

S5-01-04 Cholesterolemia mediates brain APOE expression which may contribute to brain amyloidosis

Miguel A. Papolla, Lorenzo Refolo, Javier Pacheco, Suzana Petancesca

Journal:

Neurobiology of Aging

Année:

2004

Langue:

english

Fichier:

PDF, 163 KB

english, 2004

18

Optimizing the use of CROs by academia and small companies

Lane, Rachel F., Friedman, Lauren G., Keith, Curtis, Braithwaite, Steven P., Frearson, Julie A., Lowe, David A., Longo, Frank M., Refolo, Lorenzo M., Watterson, D. Martin, Tsaioun, Katya, Shineman, Di

Journal:

Nature Reviews Drug Discovery

Année:

2013

Langue:

english

Fichier:

PDF, 103 KB

english, 2013

19

International Alzheimer's Disease Research Portfolio (IADRP) aims to capture global Alzheimer's disease research funding

Liggins, Charlene, Snyder, Heather M., Silverberg, Nina, Petanceska, Suzana, Refolo, Lorenzo M., Ryan, Laurie, Carrillo, Maria C.

Journal:

Alzheimer's & Dementia

Année:

2014

Langue:

english

Fichier:

PDF, 993 KB

english, 2014

20

Female gonadal hormone status controls the metabolism of brain amyloid β peptides

Petanceska, Suzana S., Duff, Karen, Frail, Donald E., Nagy, Vanja, Refolo, Lorenzo M., Gandy, Sam

Journal:

Neurobiology of Aging

Année:

2000

Langue:

english

Fichier:

PDF, 190 KB

english, 2000

21

Partnerships Between Philanthropy, Government and Investors are Needed to Advance Drug Discovery for Neurodegenerative Diseases

Refolo, Lorenzo, Fillit, Howard

Journal:

Current Alzheimer Research

Année:

2006

Langue:

english

Fichier:

PDF, 25 KB

english, 2006

22

Introduction: Advancing Drug Discovery for Alzheimers Disease [ ISOA Fifth Annual Investigators Meeting “Recent Advances in Drug Discovery and Development for Alzheimers Disease” Sponsored by Elan Pharmaceuticals Inc, The Graphic Expression, Glaxo Smith Kline Pharmaceuticals, Neurochem Inc, Pfizer Inc. (Guest Editors: Howard M. Fillit and Lorenzo M. Refolo)]

Fillit, Howard, Refolo, Lorenzo

Journal:

Current Alzheimer Research

Année:

2005

Langue:

english

Fichier:

PDF, 190 KB

english, 2005

23

NIA Commentary: Translational Issues in Alzheimer’s Disease Drug Development

Buckholtz, Neil S, Ryan, Laurie M, Petanceska, Suzana, Refolo, Lorenzo M

Journal:

Neuropsychopharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 135 KB

english, 2012

24

Modulation of Alzheimers Amyloidosis by Statins: Mechanisms of Action

Petanceska, Suzana, Pappolla, Miguel, Refolo, Lorenzo

Journal:

Current Medicinal Chemistry - Immunology Endocrine & Metabolic Agents

Année:

2003

Langue:

english

Fichier:

PDF, 136 KB

english, 2003

25

Guidelines to improve animal study design and reproducibility for Alzheimer's disease and related dementias: For funders and researchers

Snyder, Heather M., Shineman, Diana W., Friedman, Lauren G., Hendrix, James A., Khachaturian, Ara, Le Guillou, Ian, Pickett, James, Refolo, Lorenzo, Sancho, Rosa M., Ridley, Simon H.

Journal:

Alzheimer's & Dementia

Année:

2016

Langue:

english

Fichier:

PDF, 603 KB

english, 2016

26

Opportunities for global landscape portfolio analysis of funded research: Update on international Alzheimer's disease research portfolio (IADRP)

Liggins, Charlene, Snyder, Heather, Silverberg, Nina, Refolo, Lorenzo, Sancho, Rosa, Chambers, Larry William, Sen, Nalini

Journal:

Alzheimer's & Dementia

Année:

2015

Langue:

english

Fichier:

PDF, 47 KB

english, 2015

27

A Librarian’s Role in Improving Rigor in Research—AlzPED: Alzheimer’s Disease Preclinical Efficacy Database

Sheffield, Cynthia L., Refolo, Lorenzo M., Petanceska, Suzana S., King, R. James

Journal:

Science & Technology Libraries

Année:

2017

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2017

28

P4-075: ALZPED: A NEW DATA RESOURCE FOR IMPROVING THE RIGOR, TRANSPARENCY, REPRODUCIBILITY AND TRANSLATION OF ALZHEIMER'S DISEASE PRECLINICAL RESEARCH

Refolo, Lorenzo M., Chakroborty, Shreaya, Martin, Zane, Sheffield, Cindy, Petanceska, Suzana S.

Journal:

Alzheimer's & Dementia

Année:

2019

Fichier:

PDF, 102 KB

2019